Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects-Reference-Cited by-同舟云学术

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Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects

Published:2016-03-07 Issue:4 Volume:23 Page:286-292
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Shukla Siddharth,Schmidt Jens C,Goldfarb Katherine C,Cech Thomas R,Parker Roy

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsmb.3184.pdf

Reference32 articles.

1. Blackburn, E.H. & Collins, K. Telomerase: an RNP enzyme synthesizes DNA. Cold Spring Harb. Perspect. Biol. 3, a003558 (2011).

2. Armanios, M. & Blackburn, E.H. The telomere syndromes. Nat. Rev. Genet. 13, 693–704 (2012).

3. Heiss, N.S. et al. X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions. Nat. Genet. 19, 32–38 (1998).

4. Vulliamy, T. et al. The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita. Nature 413, 432–435 (2001).

5. Mitchell, J.R., Wood, E. & Collins, K. A telomerase component is defective in the human disease dyskeratosis congenita. Nature 402, 551–555 (1999).

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