The impact of infection and tissue damage in solid-organ transplantation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
http://www.nature.com/articles/nri3215.pdf
Reference110 articles.
1. Fishman, J. A. & Issa, N. C. Infection in organ transplantation: risk factors and evolving patterns of infection. Infect. Dis. Clin. North Am. 24, 273–283 (2010). A recent review describing the spectrum of infections that occur after solid-organ transplantation. This range reflects the impact of the use of increasingly potent immunosuppressive drugs and antimicrobial prophylaxis, as well as improved diagnosis.
2. Ahmed, E. B., Alegre, M. L. & Chong, A. S. Role of bacterial infections in allograft rejection. Expert Rev. Clin. Immunol. 4, 281–293 (2008).
3. Jamieson, A. M., Yu, S., Annicelli, C. H. & Medzhitov, R. Influenza virus-induced glucocorticoids compromise innate host defense against a secondary bacterial infection. Cell Host Microbe 7, 103–114 (2010). This study demonstrates that viral infections can trigger the release of endogenous glucocorticoids that protect against pro-inflammatory cytokine-mediated lethality but also result in systemic immunosuppression and compromised host defence against secondary bacterial infection.
4. Silverman, M. N., Pearce, B. D., Biron, C. A. & Miller, A. H. Immune modulation of the hypothalamic–pituitary–adrenal (HPA) axis during viral infection. Viral Immunol. 18, 41–78 (2005).
5. Ruzek, M. C., Miller, A. H., Opal, S. M., Pearce, B. D. & Biron, C. A. Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection. J. Exp. Med. 185, 1185–1192 (1997).
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