Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
http://www.nature.com/articles/nri1502.pdf
Reference123 articles.
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2. Atkinson, M. A. & Leiter, E. H. The NOD mouse model of type 1 diabetes: as good as it gets? Nature Med. 5, 601–604 (1999).
3. Bach, J. F. Insulin-dependent diabetes mellitus as an autoimmune disease. Endocr. Rev. 15, 516–542 (1994).
4. Haskins, K. & McDuffie, M. Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone. Science 249, 1433–1436 (1990).
5. Wegmann, D. R., Norbury-Glaser, M. & Daniel, D. Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice. Eur. J. Immunol. 24, 1853–1857 (1994).
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