A reality check of the accelerated approval of immune-checkpoint inhibitors
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology
Link
http://www.nature.com/articles/s41571-019-0260-y.pdf
Reference11 articles.
1. Rodriguez Fernandez, C. Are PD-1 and PD-L1 checkpoint inhibitors as good as we thought? Labiotech.eu https://labiotech.eu/features/pd-1-pd-l1-checkpoint-inhibitors/ (2018).
2. Tang, J. et al. The clinical trial landscape for PD1/PDL1 immune checkpoint inhibitors. Nat. Rev. Drug Discov. 17, 854 (2018).
3. Haslam, A. & Prasad, V. Estimation of the percentage of US patients with cancer who are eligible for and respond to checkpoint inhibitor immunotherapy drugs. JAMA Netw. Open. 2, e192535–e192535 (2019).
4. FDA. Drugs@FDA: FDA Approved Drug Products. FDA.gov https://www.accessdata.fda.gov/scripts/cder/daf/ (2019).
5. Gyawali, B. & Kesselheim, A. S. Reinforcing the social compromise of accelerated approval. Nat. Rev. Clin. Oncol. 15, 596–597 (2018).
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