Haplotype blocks and linkage disequilibrium in the human genome
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg1123.pdf
Reference98 articles.
1. Pritchard, J. K. & Przeworski, M. Linkage disequilibrium in humans: models and data. Am. J. Hum. Genet. 69, 1–14 (2001). This paper discusses ways of quantifying LD, and explores how LD is affected by different demographic models.
2. Devlin, B. & Risch, N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics 29, 311–322 (1995).
3. Cardon, L. R. & Abecasis, G. R. Using haplotype blocks to map human complex trait loci. Trends Genet. 19, 135–140 (2003).
4. Jorde, L. B. Linkage disequilibrium and the search for complex disease genes. Genome Res. 10, 1435–1444 (2000).
5. Ardlie, K. G., Kruglyak, L. & Seielstad, M. Patterns of linkage disequilibrium in the human genome. Nature Rev. Genet. 3, 299–309 (2002).
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