Overexpression of ABCB1 as prediction marker for CML: How close we are to translation into clinics?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
https://www.nature.com/articles/leu2016266.pdf
Reference8 articles.
1. Eadie LN, Dang P, Saunders VA, Yeung DT, Osborn MP, Grigg AP et al. The clinical significance of ABCB1 overexpression in predicting outcome of CML patients undergoing first-line imatinib treatment. Leukemia 2016; e-pub ahead of print 15 July 2016; doi:10.1038/leu.2016.179.
2. Wang L, Giannoudis A, Lane S, Williamson P, Pirmohamed M, Clark RE . Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia. Clin Pharmacol Ther 2008; 83: 258–264.
3. White DL, Dang P, Engler J, Frede A, Zrim S, Osborn M et al. Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic phase chronic myeloid leukemia treated with imatinib. J Clin Oncol 2010; 28: 2761–2767.
4. Razga F, Racil Z, Machova Polakova K, Buresova L, Klamova H, Zackova D et al. The predictive value of human organic cation transporter 1 and ABCB1 expression levels in different cell populations of patients with de novo chronic myelogenous leukemia. Int J Hematol 2011; 94: 303–306.
5. Racil Z, Razga F, Buresova L, Jurcek T, Dvorakova D, Zackova D et al. The assessment of human organic cation transporter 1 (hOCT1 mRNA expression in patients with chronic myelogenous leukemia is affected by the proportion of different cells types in the analyzed cell population. Am J Hematol 2010; 85: 525–528.
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