GPCRmd uncovers the dynamics of the 3D-GPCRome
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Published:2020-07-13
Issue:8
Volume:17
Page:777-787
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ISSN:1548-7091
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Container-title:Nature Methods
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language:en
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Short-container-title:Nat Methods
Author:
Rodríguez-Espigares IsmaelORCID, Torrens-Fontanals MarionaORCID, Tiemann Johanna K. S.ORCID, Aranda-García DavidORCID, Ramírez-Anguita Juan Manuel, Stepniewski Tomasz Maciej, Worp Nathalie, Varela-Rial Alejandro, Morales-Pastor Adrián, Medel-Lacruz Brian, Pándy-Szekeres Gáspár, Mayol EduardoORCID, Giorgino ToniORCID, Carlsson Jens, Deupi XavierORCID, Filipek Slawomir, Filizola MartaORCID, Gómez-Tamayo José Carlos, Gonzalez Angel, Gutiérrez-de-Terán HugoORCID, Jiménez-Rosés MireiaORCID, Jespers WillemORCID, Kapla JonORCID, Khelashvili GeorgeORCID, Kolb Peter, Latek DorotaORCID, Marti-Solano Maria, Matricon PierreORCID, Matsoukas Minos-TimotheosORCID, Miszta Przemyslaw, Olivella MireiaORCID, Perez-Benito Laura, Provasi Davide, Ríos SantiagoORCID, R. Torrecillas Iván, Sallander Jessica, Sztyler Agnieszka, Vasile SilvanaORCID, Weinstein HarelORCID, Zachariae UlrichORCID, Hildebrand Peter W.ORCID, De Fabritiis Gianni, Sanz FerranORCID, Gloriam David E.ORCID, Cordomi ArnauORCID, Guixà-González RamonORCID, Selent JanaORCID
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Biochemistry,Biotechnology
Reference42 articles.
1. Hauser, A. S., Attwood, M. M., Rask-Andersen, M., Schiöth, H. B. & Gloriam, D. E. Trends in GPCR drug discovery: mew agents, targets and indications. Nat. Rev. Drug Discov. 16, 829–842 (2017). 2. Munk, C. et al. GPCRdb in 2018: adding GPCR structure models and ligands. Nucleic Acids Res. 46, 440–446 (2017). 3. Munk, C. et al. An online resource for GPCR structure determination and analysis. Nat. Methods 16, 151–162 (2019). 4. Latorraca, N. R., Venkatakrishnan, A. J. & Dror, R. O. GPCR dynamics: structures in motion. Chem. Rev. 117, 139–155 (2017). 5. Hildebrand, P. W., Rose, A. S. & Tiemann, J. K. S. Bringing molecular dynamics simulation data into view. Trends Biochem. Sci. 44, 902–913 (2019).
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