Machine-learning-guided directed evolution for protein engineering
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Biochemistry,Biotechnology
Link
http://www.nature.com/articles/s41592-019-0496-6.pdf
Reference97 articles.
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3. Mandecki, W. The game of chess and searches in protein sequence space. Trends Biotechnol. 16, 200–202 (1998).
4. Pierce, N. A. & Winfree, E. Protein design is NP-hard. Protein Eng. 15, 779–782 (2002).
5. Smith, J. M. Natural selection and the concept of a protein space. Nature 225, 563–564 (1970).
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