Low-N protein engineering with data-efficient deep learning
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Biochemistry,Biotechnology
Link
http://www.nature.com/articles/s41592-021-01100-y.pdf
Reference86 articles.
1. Romero, P. A. & Arnold, F. H. Exploring protein fitness landscapes by directed evolution. Nat. Rev. Mol. Cell Biol. 10, 866–876 (2009).
2. Packer, M. S. & Liu, D. R. Methods for the directed evolution of proteins. Nat. Rev. Genet. 16, 379–394 (2015).
3. Lutz, S. & Patrick, W. M. Novel methods for directed evolution of enzymes: quality, not quantity. Curr. Opin. Biotechnol. 15, 291–297 (2004).
4. Goldsmith, M. & Tawfik, D. S. Directed enzyme evolution: beyond the low-hanging fruit. Curr. Opin. Struct. Biol. 22, 406–412 (2012).
5. Zhao, H. & Arnold, F. H. Combinatorial protein design: strategies for screening protein libraries. Curr. Opin. Struct. Biol. 7, 480–485 (1997).
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