In vivo photopharmacology with a caged mu opioid receptor agonist drives rapid changes in behavior
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Biochemistry,Biotechnology
Link
https://www.nature.com/articles/s41592-023-01819-w.pdf
Reference29 articles.
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2. Paoletti, P., Ellis-Davies, G. C. R. & Mourot, A. Optical control of neuronal ion channels and receptors. Nat. Rev. Neurosci. 20, 514–532 (2019).
3. Ankenbruck, N., Courtney, T., Naro, Y. & Deiters, A. Optochemical control of biological processes in cells and animals. Angew. Chem. Int. Ed. Engl. 57, 2768–2798 (2018).
4. Font, J. et al. Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. eLife 6, e23545 (2017).
5. López-Cano, M. et al. Remote local photoactivation of morphine produces analgesia without opioid-related adverse effects. Br. J. Pharmacol. https://doi.org/10.1111/bph.15645 (2021).
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