Systematic molecular evolution enables robust biomolecule discovery-Reference-Cited by-同舟云学术

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Systematic molecular evolution enables robust biomolecule discovery

Published:2021-12-30 Issue:1 Volume:19 Page:55-64
ISSN:1548-7091
Container-title:Nature Methods
language:en
Short-container-title:Nat Methods

Author:

DeBenedictis Erika A.^ORCID,Chory Emma J.^ORCID,Gretton Dana W.,Wang Brian,Golas Stefan,Esvelt Kevin M.^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Alfred P. Sloan Foundation

MIT Media Lab, Open Philanthropy Project, Reid Hoffman Foundation

U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Open Philanthropy Project

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Biochemistry,Biotechnology

Link

https://www.nature.com/articles/s41592-021-01348-4.pdf

Reference53 articles.

1. Good, B. H., McDonald, M. J., Barrick, J. E., Lenski, R. E. & Desai, M. M. The dynamics of molecular evolution over 60,000 generations. Nature 551, 45–50 (2017).

2. Barrick, J. E. et al. Genome evolution and adaptation in a long-term experiment with Escherichia coli. Nature 461, 1243–1247 (2009).

3. Zhao, H., Giver, L., Shao, Z., Affholter, J. A. & Arnold, F. H. Molecular evolution by staggered extension process (StEP) in vitro recombination. Nat. Biotechnol. 16, 258–261 (1998).

4. Romero, P. A. & Arnold, F. H. Exploring protein fitness landscapes by directed evolution. Nat. Rev. Mol. Cell Biol. 10, 866–876 (2009).

5. Esvelt, K. M., Carlson, J. C. & Liu, D. R. A system for the continuous directed evolution of biomolecules. Nature 472, 499–503 (2011).

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