Cell surface thermal proteome profiling tracks perturbations and drug targets on the plasma membrane
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Biochemistry,Biotechnology
Link
http://www.nature.com/articles/s41592-020-01022-1.pdf
Reference59 articles.
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2. Guan, Y. et al. Kinetics of small molecule interactions with membrane proteins in single cells measured with mechanical amplification. Sci. Adv. 1, e1500633 (2015).
3. Lomenick, B. et al. Target identification using drug affinity responsive target stability (DARTS). Proc. Natl Acad. Sci. USA 106, 21984–21989 (2009).
4. Feng, Y. et al. Global analysis of protein structural changes in complex proteomes. Nat. Biotechnol. 32, 1036–1044 (2014).
5. Savitski, M. M. et al. Tracking cancer drugs in living cells by thermal profiling of the proteome. Science 346, 1255784 (2014).
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