Sticking together the Crumbs — an unexpected function for an old friend
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm3568.pdf
Reference58 articles.
1. Tepass, U. Theres, C. & Knust, E. crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia. Cell 61, 787–799 (1990).
2. Jürgens, G., Wieschaus, E., Nüsslein-Volhard, C. & Kluding, H. Mutations affecting the pattern of larval cuticle in Drosophila. Roux' Arch. Dev. Biol. 193, 283–295 (1984).
3. Wodarz, A., Grawe, F. & Knust, E. CRUMBS is involved in the control of apical protein targeting during Drosophila epithelial development. Mech. Dev. 44, 175–187 (1993).
4. Bulgakova, N. A. & Knust, E. The Crumbs complex: from epithelial-cell polarity to retinal degeneration. J. Cell Sci. 122, 2587–2596 (2009).
5. den Hollander, A. I. et al. Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12). Nature Genet. 23, 217–221 (1999).
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