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DNA Pooling: a tool for large-scale association studies

Published:2002-11 Issue:11 Volume:3 Page:862-871
ISSN:1471-0056
Container-title:Nature Reviews Genetics
language:en
Short-container-title:Nat Rev Genet

Author:

Sham Pak,Bader Joel S.,Craig Ian,O'Donovan Michael,Owen Michael

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics,Molecular Biology

Link

http://www.nature.com/articles/nrg930.pdf

Reference80 articles.

1. Risch, N. J. Searching for genetic determinants in the new millennium. Nature 405, 847–856 (2002).

2. Cardon, L. R. & Bell, J. I. Association study designs for complex disease. Nature Rev. Genet. 2, 91–99 (2001).

3. Tabor, H. K., Risch, N. J. & Myers, R. M. Candidate-gene approaches for studying complex traits: practical considerations. Nature Rev. Genet. 3, 1–7 (2002).

4. Syvanen, A. C. Accessing genetic variation: genotyping single nucleotide polymorphisms. Nature Rev. Genet. 2, 930–942 (2001).This review provides a good introduction to SNP-genotyping methods.

5. Dorfman, R. The detection of defective members of large populations. Ann. Math. Stat. 14, 436–440 (1943).

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