Genome-wide characterization of the seasonal H3N2 virus in Shanghai reveals natural temperature-sensitive strains conferred by the I668V mutation in the PA subunit-Reference-Cited by-同舟云学术

Genome-wide characterization of the seasonal H3N2 virus in Shanghai reveals natural temperature-sensitive strains conferred by the I668V mutation in the PA subunit

Published:2018-10-23 Issue:1 Volume:7 Page:1-15
ISSN:2222-1751
Container-title:Emerging Microbes & Infections
language:en
Short-container-title:Emerging Microbes & Infections

Author:

Wei Dong¹²,Yu De-Ming¹²,Wang Ming-jie¹²,Zhang Dong-hua¹²,Cheng Qi-jian³,Qu Jie-Ming⁴,Zhang Xin-xin¹²⁵

Affiliation:

1. Research Laboratory of Clinical Virology, Ruijin HospitalShanghai Jiaotong University School of Medicine Shanghai China

2. Department of Infectious Diseases, Institute of Infectious and Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine Shanghai China

3. Department of Respiratory Diseases, Ruijin Hospital NorthShanghai Jiaotong University School of Medicine Shanghai China

4. Department of Respiratory Diseases, Ruijin HospitalShanghai Jiaotong University School of Medicine Shanghai China

5. Clinical Research Center, Ruijin Hospital NorthShanghai Jiaotong University School of Medicine Shanghai China

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Link

http://www.nature.com/articles/s41426-018-0172-4.pdf

Reference36 articles.

1. Global circulation patterns of seasonal influenza viruses vary with antigenic drift

2. Divergent seasonal patterns of influenza types A and B across latitude gradient in Tropical Asia

3. Characterization of Regional Influenza Seasonality Patterns in China and Implications for Vaccination Strategies: Spatio-Temporal Modeling of Surveillance Data

4. The Roles of Competition and Mutation in Shaping Antigenic and Genetic Diversity in Influenza

5. Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (flumist) derived from cold-adapted a/ann arbor/6/60

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