Hemoglobin red cell distribution width ratio as a prognostic marker in patients with locally advanced lung adenocarcinoma

Author:

KURT Hasret Gizem1ORCID,ÖZTÜRK Ayperi2ORCID,ÖZTÜRK ERGÜR Figen2ORCID

Affiliation:

1. SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ATATÜRK GÖĞÜS HASTALIKLARI VE GÖĞÜS CERRAHİSİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ

2. UNIVERSITY OF HEALTH SCIENCES, ANKARA ATATÜRK HEALTH RESEARCH CENTER FOR PULMONOLOGY AND THORACIC SURGERY

Abstract

Aims: Hemoglobin/red cell distribution width ratio (HRR) has been defined as an effective prognostic factor in various malignancies. The aim of this study is to investigate the prognostic role of HRR in locally advanced lung adenocarcinoma. Methods: 626 patients diagnosed with locally advanced lung adenocarcinoma were screened. The best cut-off point of HRR for overall survival (OS) and progression free survival (PFS) was determined by ROC analysis. A HRR cut-off value was determined, patients were classified as having lower or higher HRR. Both groups’ clinical, demographic, laboratory values were compared. To identify independent predictors of prognosis, multivariate cox regression analysis was used. Results: A total of119 patients were included. The best cut-off point of HRR in determining OS was 0.963%.HRR below the cut-off value increased mortality by 2.2fold.The group with HRR

Publisher

Anatolian Current Medical Journal

Subject

General Medicine

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