Altersabhängige Ansteuerung der Muskulatur im Stand bei Patienten mit Hämophilie

Author:

Stäuber F.,Brunner A.,Czepa D.,Krüger S.,Wendel M.,Seuser A.,Hilberg T.,Göhler S.

Abstract

SummaryThe haemophilic arthropathy affects the function of the knee joint muscles. The aim of this study was to investigate the myoelectrical signal of knee joint muscles in different age stages during upright standing. Surface EMG (SEMG) amplitudes of quadriceps, hamstrings and gastrocnemii were measured in 191 patients with severe haemophilia A (n=164) and B (n=27) while standing on an even surface. After an age-based classification of patients into the subgroups HA: 17–29 (n = 37), HB: 30–39 (n = 50), HC: 40–49 (n = 61), HD: 50–70 in years (n = 43) the clinical WFH score for the ankle and knee joint was determined. To normalize the SEMG values amplitude ratios (percentage of cumulated activity) were calculated with respect to the specific limb. With increasing age, the patient showed descriptively a deterioration of the joint situation. The extensors of the knee joint reached significantly higher absolute and percentage levels in the muscle activity with increasing age (p < 0.05). The absolute amplitude values of the Mm. gastrocnemii showed no differences in the age groups while the relative levels were decreased.The present study shows that patients with increasing age and degree of haemophilic arthro pathy deve lop a modified control strategy during upright standing, in the form of a shift from the plantar flexors to the extensors of the knee joint.

Publisher

Georg Thieme Verlag KG

Subject

Hematology

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