Search for drug discovery targets focusing on cancer stroma

Author:

KAMADA Haruhiko1

Affiliation:

1. Laboratory of Biopharmaceutical Research, National Institutes of Biomedical Innovation, Health and Nutrition, 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan

Publisher

AMED iD3 Catalyst Unit

Reference51 articles.

1. 1. Edwards, A. M., Arrowsmith, C. H., Bountra, C., Bunnage, M. E., Feldmann, M., Knight, J. C., Patel, D. D., Prinos, P., Taylor, M. D., Sundström, M., SGC Open Source Target-Discovery Partnership 2015. Preclinical target validation using patient-derived cells. Nat. Rev. Drug Discov. 14: 149–150.

2. 2. Loth, E., Spooren, W., Ham, L. M., Isaac, M. B., Auriche-Benichou, C., Banaschewski, T., Baron-Cohen, S., Broich, K., Bölte, S., Bourgeron, T., Charman, T., Collier, D., de Andres-Trelles, F., Durston, S., Ecker, C., Elferink, A., Haberkamp, M., Hemmings, R., Johnson, M. H., Jones, E. J., Khwaja, O. S., Lenton, S., Mason, L., Mantua, V., Meyer-Lindenberg, A., Lombardo, M. V., O’Dwyer, L., Okamoto, K., Pandina, G. J., Pani, L., Persico, A. M., Simonoff, E., Tauscher-Wisniewski, S., Llinares-Garcia, J., Vamvakas, S., Williams, S., Buitelaar, J. K. and Murphy, D. G. 2016. Identification and validation of biomarkers for autism spectrum disorders. Nat. Rev. Drug Discov. 15: 70–73.

3. 3. Cardon, L. R. and Harris, T. 2016. Precision medicine, genomics and drug discovery. Hum. Mol. Genet. 25R2: R166–R172.

4. 4. Freiberg, C., Brötz-Oesterhelt, H. and Labischinski, H. 2004. The impact of transcriptome and proteome analyses on antibiotic drug discovery. Curr. Opin. Microbiol. 7: 451–459.

5. 5. Tavares, R., Scherer, N. M., Ferreira, C. G., Costa, F. F. and Passetti, F. 2015. Splice variants in the proteome: a promising and challenging field to targeted drug discovery. Drug Discov. Today 20: 353–360.

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