A palmitylated peptide derived from the glycoprotein Ibbeta cytoplasmic tail inhibits platelet activation
Author:
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1538-7836.2003.00478.x/fullpdf
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3. Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human platelets.
4. von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.
5. Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s)
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