Age of onset possibly associated with the degree of heteroplasmy in two male siblings with diabetes mellitus having an A to G transition at 3243 of mitochondrial DNA
Author:
Publisher
Wiley
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1464-5491.2002.00777.x/fullpdf
Reference16 articles.
1. The high prevalence of the diabetic patients with a mutation in the mitochondrial gene in Japan
2. Clinical Phenotypes, Insulin Secretion, and Insulin Sensitivity in Kindreds With Maternally Inherited Diabetes and Deafness Due to Mitochondrial tRNALeu(UUR) Gene Mutation
3. Sequence of a Variant Thyroxine-Binding Globulin(TBG) in a Family with Partial TBG Deficiency in Japanese(TBG-PDJ).
4. Sequence and organization of the human mitochondrial genome
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2. Mitochondrial–nuclear epistasis: Implications for human aging and longevity;Ageing Research Reviews;2011-04
3. Mitochondrial Manipulation as a Treatment for Aging;The Future of Aging;2010
4. Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation;Diabetic Medicine;2008-04
5. Selection against Pathogenic mtDNA Mutations in a Stem Cell Population Leads to the Loss of the 3243A→G Mutation in Blood;The American Journal of Human Genetics;2008-02
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