Oxidation Products Arising from the Action of Monoamine Oxidase B on 1-Methyl-4-Benzyl-1,2,3,6-Tetrahydropyridine, a Nonneurotoxic Analogue of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine

Author:

Sablin Sergey O.,Krueger Matthew J.,Bachurin Sergey O.,Solyakov Lev S.,Efange Simon M. N.,Singer Thomas P.

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference21 articles.

1. The role of dopamine-uptake system in the development of experimental parkinsonism induced by MPTP and its analogs;Bachurin;Dokl. Acad. Nauk SSSR,1989

2. Molecular basis of discrepancies in neurotoxic properties among 1-methyl-4-aryl-1,2,3,6-tetrahydropyridines;Bachurin;Mol. Chem. Neuropathol.,1992

3. Olefin oxidation;Bateman;Q. Rev. Chem. Soc.,1954

4. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase;Chiba;Biochem. Biophys. Res. Commun.,1984

5. Flexible N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogues: synthesis and monoamine oxidase catalyzed bioactivation;Efange;J. Med. Chem.,1990

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