From toxin to adjuvant: the rational design of a vaccine adjuvant vector, CTA1-DD/ISCOM

Author:

Lycke Nils

Publisher

Hindawi Limited

Subject

Virology,Immunology,Microbiology

Reference61 articles.

1. Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit;Agren;J Immunol,1997

2. Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity;Agren;J Immunol,1999

3. The ADP-­ribosylating CTA1-DD adjuvant enhances T cell-dependent and independent responses by direct action on B cells involving anti-apoptotic Bcl-2- and germinal center-­promoting effects;Agren;J Immunol,2000

4. Control of adaptive immune responses by Toll-like receptors;Barton;Curr Opin Immunol,2002

5. The level of protection against rotavirus shedding in mice following immunization with a chimeric VP6 protein is dependent on the route and the coadministered adjuvant;Choi;Vaccine,2002

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