Are Anti-BP180 IgG1 or IgG4 Autoantibodies Pathogenic?

Author:

Liu Zhi

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference18 articles.

1. Immunoblot analysis of IgG subclasses of circulating antibodies in bullous pemphigoid;Bernard;Clin Immunol Immunopathol,1990

2. Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera Immunolocalization of this protein to the hemidesmosome;Diaz;J Clin Invest,1990

3. IgG4 and IgE are the major immunoglobulins targeting the NC16A domain of BP180 in Bullous pemphigoid: serum levels of these immunoglobulins reflect disease activity;Dopp;J Am Acad Dermatol,2000

4. An in vitro model of immune complex-mediated basement membrane zone separation caused by pemphigoid antibodies, leukocytes, and complement;Gammon;J Invest Dermatol,1982

5. Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BP180 ectodomain;Giudice;J Immunol,1993

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