Analysis of Tumor Cell Evolution in a Melanoma: Evidence of Mutational and Selective Pressure for Loss of p16ink4 and for Microsatellite Instability

Author:

Rübben Albert,Babilas Philipp,Baron Jens M.,Hofheinz Anja,Neis Mark,Sels Florian,Sporkert Markus

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference33 articles.

1. A mismatch recognition defect in colon carcinoma confers DNA microsatellite instability and a mutator phenotype;Aquilina;Proc Natl Acad Sci USA,1994

2. Deletion mapping of two potential chromosome 14 tumor suppressor gene loci in ovarian carcinoma;Bandera;Cancer Res,1997

3. The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis;Bartkova;Cancer Res,1996

4. Microallelotyping defines the sequence and tempo of allelic losses at tumour suppressor gene loci during colorectal cancer progression;Boland;Nat Med,1995

5. Chromosomal allele loss in primary cutaneous melanoma is heterogeneous and correlates with proliferation;Boni;J Invest Dermatol,1998

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