Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes. Kinetics and sensitivity to cytochrome P450 2D inhibitors
Author:
Publisher
Wiley
Subject
Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1432-1033.2003.03763.x/fullpdf
Reference54 articles.
1. Inhibition and Induction of Cytochrome P450 and the Clinical Implications
2. Use of In Vitro and In Vivo Data to Estimate the Likelihood of Metabolic Pharmacokinetic Interactions
3. IN VITRO AND IN VIVO DRUG INTERACTIONS INVOLVING HUMAN CYP3A
4. In Vitro Approaches to Predicting Drug Interactions In Vivo
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Elucidating the structure and cytochrome P450-mediated mechanism for novel metabolites of GDC-0575 in rats;Xenobiotica;2022-03-04
2. Basal efflux of bile acids contributes to drug-induced bile acid-dependent hepatocyte toxicity in rat sandwich-cultured hepatocytes;Toxicology in Vitro;2015-10
3. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments;Drug Metabolism and Disposition;2015-09-09
4. Fluorescence-Based Screening of Cytochrome P450 Activities in Intact Cells;Methods in Molecular Biology;2013
5. Aloe Vera Juice: IC50 and Dual Mechanistic Inhibition of CYP3A4 and CYP2D6;Phytotherapy Research;2011-08-15
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3