The inhibition of Ras farnesylation leads to an increase in p27Kip1 and G1 cell cycle arrest
Author:
Publisher
Wiley
Subject
Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1432-1033.2003.03647.x/fullpdf
Reference63 articles.
1. All ras proteins are polyisoprenylated but only some are palmitoylated
2. Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.
3. Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity.
4. Synthesis and biological activity of semipeptoid farnesyltransferase inhibitors
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Universal intracellular transducer ras and its role in the development of drosophila;Russian Journal of Developmental Biology;2013-09
2. Isoprenoids and Related Pharmacological Interventions: Potential Application in Alzheimer’s Disease;Molecular Neurobiology;2012-03-15
3. Targeting protein prenylation for cancer therapy;Nature Reviews Cancer;2011-10-24
4. RAF may induce cell proliferation through hypermethylation of tumor suppressor gene promoter in gastric epithelial cells;Cancer Science;2009-01
5. The farnesyltransferase inhibitor, LB42708, inhibits growth and induces apoptosis irreversibly in H-ras and K-ras-transformed rat intestinal epithelial cells;Toxicology and Applied Pharmacology;2006-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3