Costimulation of CD28- T Cells Through CD3 and beta1-Integrins Induces a Limited Th1 Cytokine Response
Author:
Publisher
Wiley
Subject
Immunology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1365-3083.1999.00562.x/fullpdf
Reference33 articles.
1. CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes.
2. CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.
3. CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
4. CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines.
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1. VLA-4 integrin concentrates at the peripheral supramolecular activation complex of the immune synapse and drives T helper 1 responses;Proceedings of the National Academy of Sciences;2004-07-19
2. Acute Cellular Rejection Following Human Heart Transplantation is Associated with Increased Expression of Vitronectin Receptor (Integrin αvβ3);American Journal of Transplantation;2002-02
3. Costimulation by Extracellular Matrix Proteins Determines the Response to TCR Ligation;Cellular Immunology;2001-05
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