Differential Expression and Modulation of Costimulatory Molecules CD80 and CD86 on Monocytes from Patients with Systemic Lupus Erythematosus
Author:
Publisher
Wiley
Subject
Immunology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1365-3083.1999.00452.x/fullpdf
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1. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.
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3. B70 antigen is a second ligand for CTLA-4 and CD28
4. Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation
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