Discrepancy in plasma melarsoprol concentrations between HPLC and bioassay methods in patients with T. gambiense sleeping sickness indicates that melarsoprol is metabolized-Reference-Cited by-同舟云学术

Discrepancy in plasma melarsoprol concentrations between HPLC and bioassay methods in patients with T. gambiense sleeping sickness indicates that melarsoprol is metabolized

Published:1998-11 Issue:11 Volume:3 Page:913-917
ISSN:1360-2276
Container-title:Tropical Medicine & International Health
language:en
Short-container-title:Tropical Medicine & International Health

Author:

Bronner ¹,Brun ²,Doua ¹,Ericsson ³,Burri ²,Keiser ²,Miézan ⁴,Boa ⁵,Rombo ¹,Gustafsson ¹

Affiliation:

1. Divisions of Clinical Pharmacology and Infectious Diseases, Karolinska Institute, Huddinge, Sweden

2. Swiss Tropical Institute, Basel, Switzerland

3. Pharmacy, Huddinge University Hospital, Huddinge, Sweden

4. Projet de Recherches Cliniques sur la Trypanosomiase, Daloa, Côte d'Ivoire

5. Service de Neurologie du Centre Hospitalier Universitaire de Cocody, Abidjan, Côte d'Ivoire

Publisher

Wiley

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,Parasitology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-3156.1998.00327.x

Reference16 articles.

1. In vivo effects of α-dl-Difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei

2. Pharmacokinetics and adverse reactions after a single dose of pentamidine in patients with Trypanosoma gambiense sleeping sickness.

3. Pharmacokinetic Properties of the Trypanocidal Drug Melarsoprol

4. Alternative application of melarsoprol for treatment of T.b. gambiense sleeping sickness.;Burri C;Annales de la Societé Belge Médecine Tropicale,1995

5. An in vitro bioassay for quantification of melarsoprol in serum and cerebrospinal fluid.;Burri C;Tropical Medicine and Parasitology,1992

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