90K (Mac-2 BP) in human milk-Reference-Cited by-同舟云学术

90K (Mac-2 BP) in human milk

Published:1996-06 Issue:3 Volume:104 Page:543-546
ISSN:1365-2249
Container-title:Clinical and Experimental Immunology
language:en
Short-container-title:

Author:

D’Ostilio N¹,Sabatino G²,Natoli C¹,Ullrich A³,Iacobelli S¹

Affiliation:

1. Cattedra di Oncologia Medica and

2. Cattedra di Neonatologia, Università‘G. D’Annunzio’, Chieti, Italy

3. Department of Molecular Biology, Max-Planck Institut fu¨r Biochemie, Martinsried, Germany

Abstract

SUMMARY Human 90K, also known as Mac-2 binding protein (Mac-2 BP), is a secreted glycoprotein which is widely expressed, binds to the human macrophage-associated lectin Mac-2, and may have a role in host defence. We have measured the concentrations of 90K in human breast milk from eight healthy mothers delivering mature healthy infants after full-term pregnancy using a specific immunoenzymatic assay. Maximal 90K concentrations were observed on days 2–3 post-partum, and ranged from 13.4 to 79.2 μg/ml. The concentrations of 90K in the milk had no correlation with those in the maternal blood.

Publisher

Oxford University Press (OUP)

Subject

Immunology,Immunology and Allergy

Link

https://academic.oup.com/cei/article-pdf/104/3/543/42203871/j.1365-2249.1996.40745.x.pdf

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