B‐lymphocyte suppression in multiple myeloma is a reversible phenomenon specific to normal B‐cell progenitors and plasma cell precursors

Author:

Rawstron Andrew C.1,Davies Faith E.1,Owen Roger G.1,English Anne1,Pratt Guy1,Child J. Anthony1,Jack Andrew S.1,Morgan Gareth J.1

Affiliation:

1. Department of Haematology, The General Infirmary at Leeds, Leeds

Publisher

Wiley

Subject

Hematology

Reference30 articles.

1. Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell

2. CD34+ circulating B cells in multiple myeloma have a rearranged IgH VDJ identical to that of autologous plasma cells as quantitated by in‐situ RT‐PCR;Belch A.R.;Blood,1996

3. In multiple myeloma, clonotypic B lymphocytes are detectable among CD19+ peripheral blood cells expressing CD38, CD56, and monotypic Ig light chain;Bergsagel P.L.;Blood,1995

4. The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell.

5. Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients;Billadeau D.;Blood,1992

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