Activity‐dependent regulation of muscle genes: repressive and stimulatory effects of innervation
Author:
Affiliation:
1. Unit of Molecular and Neurobiology, Laboratory of Developmental Neurobiology, National Institute of Child Health and Human Development, Bethesda, MD, USA
2. Pathologisches Institut der Universitat, Bern, Switzerland
Publisher
Wiley
Subject
Physiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-201X.1998.1630s3S17.x
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1. cis-acting sequences of the rat troponin I slow gene confer tissue- and development-specific transcription in cultured muscle cells as well as fiber type specificity in transgenic mice.
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3. In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus.
4. Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death
5. Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization.
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