Differential recognition of obligate anaerobic bacteria by human mannose-binding lectin-Reference-Cited by-同舟云学术

Differential recognition of obligate anaerobic bacteria by human mannose-binding lectin

Published:2001-05 Issue:2 Volume:124 Page:223-228
ISSN:1365-2249
Container-title:Clinical and Experimental Immunology
language:en
Short-container-title:

Author:

Townsend R¹,Read R C¹,Turner M W²,Klein N J²,Jack D L¹²

Affiliation:

1. Division of Genomic Medicine, University of Sheffield, United Kingdom

2. Immunobiology Unit, Institute of Child Health, University College London, UK

Abstract

SUMMARY Deficiency of the innate, humoral immune component mannose-binding lectin (MBL) predisposes individuals to a variety of infections, but the importance of MBL in infection by anaerobes has not been addressed. The attachment of MBL to a wide range of anaerobic bacteria associated with human disease and colonization was surveyed. The results suggest that for the species we examined, resistance to MBL binding may be associated with organisms that are more commonly pathogenic and that MBL binding to some bacteria may be phase variable.

Publisher

Oxford University Press (OUP)

Subject

Immunology,Immunology and Allergy

Link

https://academic.oup.com/cei/article-pdf/124/2/223/42163070/j.1365-2249.2001.01549.x.pdf

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