A phase II trial of pirfenidone (5-methyl-1-phenyl-2-[1H]-pyridone), a novel anti-fibrosing agent, in myelofibrosis with myeloid metaplasia

Author:

Mesa Ruben A.,Tefferi Ayalew,Elliott Michelle A.,Hoagland H. Clark,Call Timothy G.,Schroeder Georgene S.,Yoon Soo-Young,Li Chin-Yang,Gray Leigh A.,Margolin S.,Hook C. Christopher

Publisher

Wiley

Subject

Hematology

Reference12 articles.

1. The Italian consensus conference on diagnostic criteria for myelofibrosis with myeloid metaplasia;Barosi;British Journal of Haematology,1999

2. Inhibition of tumor necrosis factor and subsequent endotoxin shock by pirfenidone;Cain;International Journal of Immunopharmacology,1998

3. Prognostic factors in agnogenic myeloid metaplasia: a report on 195 cases with a new scoring system;Dupriez;Blood,1996

4. Pirfenidone inhibits PDGF isoforms in bleomycin hamster model of lung fibrosis at the translational level;Gurujeyalakshmi;American Journal of Physiology,1999

5. Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis;Iyer;Journal of Pharmacology and Experimental Therapeutics,1999

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