Autoreactive cytotoxic T cells in mice are induced by immunization with a conserved mitochondrial enzyme in Freund’s complete adjuvant
Author:
Affiliation:
1. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2567.1999.00762.x
Reference39 articles.
1. 1C.C.A. Bernard, T.E. Mandel, and I.R. MacKay, 1992 Experimental models of human autoimmune disease: Overview and prototypes. In:The Autoimmune Diseases II(eds N. R. Rose & I. R. Mackay), p. 47. Academic Press, Orlando.
2. CD8 cytotoxic T-cell clone rapidly transfers autoimmune diabetes in very young NOD and MHC class I-compatible scid mice
3. Reduced Incidence and Delayed Onset of Diabetes in Perforin-deficient Nonobese Diabetic Mice
4. ?Self? to cytotoxic T cells has to be 1 000 or less high affinity nonapeptides per MHC antigen
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