Rectal tissue, plasma and urine concentrations of mesalazine after single and multiple administrations of 500 mg suppositories to healthy volunteers and ulcerative proctitis patients

Author:

Aumais G.,Lefebvre M.,Tremblay C.,Bitton A.,Martin F.,Giard A.,Madi M.,Spénard J.

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Reference12 articles.

1. Double-blind, placebo-controlled evaluation of 5-ASA suppositories in active distal proctitis and measurement of extent of spread using 99mTc-labeled 5-ASA suppositories;William;Dig Dis Sci,1987

2. 5-aminosalicylic acid enema (Pentasa) versus hydrocortisone acetate foam (Proctocort) for the treatment of outbreaks of proctitis and cryptogenetic proctosigmoiditis. A comparative randomized multicenter trial;Ngo;Gastroenterol Clin Biol,1992

3. Efficacy of a daily application of mesalazine (Pentasa) suppository with progressive release, in the treatment of ulcerative proctitis. A double-blind versus placebo randomized trial;Ngo;Gastroenterol Clin Biol,1992

4. Mesalazine suppositories versus hydrocortisone foam in patients with distal ulcerative colitis. A comparison of the efficacy and practicality of two topical treatment regimens;Farup;Scand J Gastroenterol,1995

5. Long-term use of mesalazine suppositories in remission maintenance of ulcerative proctitis;Hanauer;Am J Gastroenterol,2000

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