Local and Sustained Delivery of 5-Fluorouracil from Biodegradable Microspheres for the Radiosensitization of Malignant Glioma: A Randomized Phase II Trial-Reference-Cited by-同舟云学术

Local and Sustained Delivery of 5-Fluorouracil from Biodegradable Microspheres for the Radiosensitization of Malignant Glioma: A Randomized Phase II Trial

Published:2005-02-01 Issue:2 Volume:56 Page:242-248
ISSN:0148-396X
Container-title:Neurosurgery
language:en
Short-container-title:

Author:

Menei Philippe¹,Capelle Laurent²,Guyotat Jacques³,Fuentes Stéphane⁴,Assaker Richard⁵,Bataille Benoit⁶,François Patrick⁷,Dorwling-Carter Didier⁸,Paquis Philippe⁹,Bauchet Luc¹⁰,Parker Fabrice¹¹,Sabatier Jean¹²,Faisant Nathalie¹³,Benoit Jean-Pierre¹³

Affiliation:

1. Department of Neurosurgery, Institut National de la Santé et de la Recherche Médicale, Unite 646, University Hospital, Angers, France

2. Department of Neurosurgery, University Hospital Pitié-Salpétrière, Paris, France

3. Department of Neurosurgery, University Hospital, Hospice de Lyon, Lyon, France

4. Department of Neurosurgery, University Hospital, Marseille, France

5. Department of Neurosurgery, University Hospital, Lille, France

6. Department of Neurosurgery, University Hospital, Poitiers, France

7. Department of Neurosurgery, University Hospital, Tours, France

8. Department of Neurosurgery, General Hospital, Orléans, France

9. Department of Neurosurgery, University Hospital, Nice, France

10. Department of Neurosurgery, University Hospital, Montpellier, France

11. Department of Neurosurgery, University Hospital, Kremlin Bicêtre, France

12. Department of Neurosurgery, University Hospital, Toulouse, France

13. Institut National de la Santé et de la Recherche Médicale, Unite 646, University of Angers, Angers France

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Clinical Neurology,Surgery

Link

http://academic.oup.com/neurosurgery/article-pdf/56/2/242/24487606/00006123-200502000-00009.pdf

Reference23 articles.

1. Preparation of biodegradable 5-fluorouracil-loaded microspheres;Boisdron-Celle;J Pharm Pharmacol,1995

2. Clinical trial end points in malignant glioma: Need for effective trial design strategy;Brada;Sem Oncol,2000

3. Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas: Polymer-Brain Tumor Treatment Group;Brem;Lancet,1995

4. PLGA-based microparticles: Elucidation of mechanisms and a new, simple mathematical model quantifying drug release;Faisant;Eur J Pharm Sci,2002

5. Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults;Fine;Cancer,1993

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