PRIMARY INTRAMEDULLARY MELANOCYTOMA OF THE SPINAL CORD

Author:

Karikari Isaac O.1,Powers Ciaran J.1,Bagley Carlos A.1,Cummings Thomas J.2,Radhakrishnan Senthilkumar1,Friedman Allan H.1

Affiliation:

1. Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina

2. Department of Pathology, Duke University Medical Center, Durham, North Carolina

Abstract

Abstract OBJECTIVE The authors report 2 cases of primary intramedullary spinal melanocytomas in 2 patients who presented with lower extremity numbness and/or weakness. CLINICAL PRESENTATION Magnetic resonance imaging of the spine, thoracic laminectomy, and histological examination revealed the diagnosis. TECHNIQUE Microscopic and immunohistochemical analysis revealed the diagnosis of primary melanocytoma. CONCLUSION Melanocytomas of the spine are rare lesions without distinctive imaging characteristics and pose a preoperative diagnostic challenge. A review of the relevant literature and clinical behavior of this uncommon tumor entity is provided.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical),Surgery

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3. Pigmented tumors of the central nervous system;Bakody;Cleve Clin Q,1950

4. Intramedullary meningeal melanocytoma [in French];Barth;Neurochirurgie,1993

5. Crush cytology of melanocytoma of spinal cord: A case report;Chen;Acta Cytol,2003

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