Affiliation:
1. Stroke Registry of Dijon (INSERM and Institut de Veille Sanitaire), University Hospital and Faculty of Medicine and Department of Neurology, Dijon, France
2. Department of Neurosurgery, University Hospital, Dijon, France
3. Department of Neuroimaging, University Hospital, Dijon, France
Abstract
Abstract
BACKGROUND
Subarachnoid hemorrhage accounts for 2% to 5% of all strokes and is associated with high morbidity and mortality rates. Reports in the literature show that case-fatality rates vary with time and according to geographical area.
OBJECTIVE
The objective of the study was to evaluate the case-fatality rates in subarachnoid hemorrhage at 1 and 6 months and to determine trends in these rates over 22 years using a population-based registry.
METHODS
The Dijon Stroke Registry has enabled us to perform a comprehensive analysis of subarachnoid hemorrhage diagnosed in a population of >150 000 inhabitants hospitalized between 1985 and 2006 in the Dijon University Hospital, which has both a neurosurgery unit and a neuroradiology unit. Diagnosis was based on clinical and neuroimaging features and, when necessary, on lumbar puncture.
RESULTS
Case-fatality rates for hospitalized subarachnoid hemorrhages at 1 and 6 months were 15.59% (95% confidence interval [CI], 9.37–25.34) and 16.84% (95% CI, 10.33–26.78), respectively. From 1985 to 1995, case-fatality rates for SAH at 1 and 6 months were 17.1% (95% CI, 8.1–34.2) and 17.7% (95% CI, 9.6–31.3), whereas from 1996 to 2006, they were 20.2% (95% CI, 10.2–37.8) and 19.7% (95% CI, 11.1–33.6), respectively.
CONCLUSION
Case-fatality rates for hospitalized subarachnoid hemorrhages in this population-based study remained stable over 22 years, suggesting that this stroke subtype is still a very severe disease despite early management. Most deaths occurred during the first 30 days. Further work is necessary to evaluate levels of prehospital case-fatality in our population-based registry.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Clinical Neurology,Surgery
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