The Role of Endothelin in Experimental Cerebral Vasospasm

Author:

Roux Sébastien1,Löftier Bernd-Michael1,Gray Gillian A.1,Sprecher Urs1,Clozel Martine1,Clozel Jean-Paul1

Affiliation:

1. Pharma Division, Preclinical Research, F. FHoffmann-La Roche Ltd., Basel, Switzerland

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical),Surgery

Reference40 articles.

1. Endothelin: A potential modulator of cerebral vasospasm;Asano;Eur J Pharmacol,1990

2. ETB receptors on aortic smooth muscle cells of spontaneously hypertensive rats;Batra;Am J Physiol,1993

3. Nicorandil: Differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations—Comparisons to aprikalim (RP 52891) and nitroglycerin;Borg;J Pharmacol Exp Ther,1991

4. Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist;Clozel;J Pharmacol Exp Ther,1994

5. BQ-123, a peptidic endothelin ETA receptor antagonist, prevents the early cerebral vasospasm following subarachnoid hemorrhage after intracisternal, but not intravenous injection;Clozel;Life Sci,1993

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