Simulation of a Prolactin-secreting Adenoma by an Intrasellar Craniopharyngioma

Author:

Gamblin George T.1,James L. Patrick1,Thomas John1,Six Eric1,Eil Charles1

Affiliation:

1. Departments of Medicine, Pathology, Radiology, and Neurosurgery, National Naval Medical Center and Uniformed Services University of the Health Sciences, Bethesda, Maryland

Abstract

Abstract We report here an unusual case of a 21-year-old woman who presented with amenorrhea, galactorrhea, and hyperprolactinemia (66 to 81 ng/ml) secondary to an unsuspected intrasellar craniopharyngioma. The results of preoperative endocrine testing were compatible with the presence of a prolactin-secreting adenoma. Moreover, high resolution computed tomographic scanning revealed an uncalcified hypodense sellar mass that did not enhance after contrast administration, a feature shared by many prolactinomas. This report illustrates that amenorrhea, galactorrhea, mild to moderate hyperprolactinemia, and a sellar mass should not automatically be attributed to the presence of a prolactin-secreting adenoma.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical),Surgery

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Tumors of the Sellar Region Mimicking Pituitary Adenomas;Experimental and Clinical Endocrinology & Diabetes;2009-07-15

2. Rapid enlargement and recurrence of a preexisting intrasellar craniopharyngioma during the course of two pregnancies;Journal of Neurosurgery;1999-08

3. Transsphenoidal microsurgery for craniopharyngioma;Surgical Neurology;1992-03

4. Gonadotroph Adenoma of the Pituitary Mimicking a Prolactinoma;Neurosurgery;1991-03-01

5. Differential Diagnosis of Pituitary Tumors;Endocrinology and Metabolism Clinics of North America;1987-09

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