Cerebral Gliosarcomas: Correlation of Computed Tomographic Findings, Surgical Aspect, Pathological Features, and Prognosis

Author:

Maiuri Francesco1,Stella Lucio1,Benvenuti Dino1,Giamundo Arcangelo1,Pettinato Guido1

Affiliation:

1. Institutes of Neurosurgery and Pathology, 2nd School of Medicine, University of Naples, Naples, Italy

Abstract

Abstract The cases of 5 patients with cerebral gliosarcomas examined by computed tomography are reported and the correlations among the computed tomographic (CT) findings, the surgical and histological aspects, and the prognosis are discussed. In some patients, these tumors appear on CT scan as intracerebral lesions, with large necrotic areas and peripheral contrast enhancement; this CT aspect, similar to that of glioblastomas, corresponds to a diffusely infiltrating growth of the tumor and the prevalence of a gliomatous component. In other patients, the tumor appears on the CT scan as a hyperdense mass with well-defined margins and homogenous contrast enhancement;; this CT finding, which may mimic that of a meningioma, corresponds to a rather well-demarcated surgical aspect and the prevalence of sarcomatous component. In our series, we have also noticed a more prolonged survival in a patient with a CT aspect that suggested a meningioma and prevalence of the sarcomatous component.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Clinical Neurology,Surgery

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