Antisense Expression of Protein Kinase Cα Inhibits the Growth and Tumorigenicity of Human Glioblastoma Cells

Author:

Ahmad Shakeel1,Mineta Toshihiro2,Martuza Robert L.2,Glazer Robert I.1

Affiliation:

1. Departments of Pharmacology, Georgetown University Medical Center, Washington, D.C.

2. Neurosurgery, Georgetown University Medical Center, Washington, D.C.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical),Surgery

Reference27 articles.

1. Expression of the antisense cDNA for protein kinase Cα attenuates resistance in doxorubicin-resistant MCF-7 breast carcinoma cells;Ahmad;Mol Pharmacol,1993

2. The role of protein kinase C in the modulation of multidrug resistance: Expression of the atypical gamma isoform of protein kinase C does not confer increased resistance to doxorubicin;Ahmad;Mol Pharmacol,1992

3. Molecular cloning and characterization of PKCϕ, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells;Baier;J Biol Chem,1993

4. Decrease in phorbol ester receptors in human brain tumors;Battaini;Eur Neurol,1990

5. Expression pattern of α-protein kinase C in human astrocytomas indicates a role in malignant progression;Benzil;Cancer Res,1992

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