Desmoplastic Medulloblastoma Metastatic to the Pancreas: Case Report

Author:

Krouwer Hendrikus G.J.1,Vollmerhausen John23,White Joel23,Prados Michael D.1

Affiliation:

1. Neuro-Oncology Service, Brain Tumor Research Center, Department of Neurological Surgery, School of Medicine, University of California, San Francisco, California

2. Departments of Neurology and Hematology/Oncology, Kaiser Permanente Medical Group, Walnut Creek, California

3. Radiation Oncology Center, Walnut Creek, California

Abstract

Abstract A case is reported in which a desmoplastic medulloblastoma metastasized to the pancreas and to the surrounding soft tissues but did not recur locally or disseminate within the central nervous system. Multidrug chemotherapy and local radiation therapy resulted in a complete remission. In all four previously reported cases of medulloblastoma metastasizing to the pancreas, the diagnosis was not made until the postmortem examination, and all of these patients also had extensive metastases in other organ systems. Modification of the Weiss criteria defining extraneural metastases from tumors of the central nervous system is suggested.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Neurology (clinical),Surgery

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