Affiliation:
1. Sechenov First Moscow State Medical University (Sechenov University)
Abstract
Aim. The study reviews current evidence on digestive system lesions provoked by the new COVID-19 coronavirus infection.Key points. Alongside the destructive impact on respiratory system, COVID-19 manifests itself in gastrointestinal symptoms (nausea, vomiting, diarrhoea) that may precede respiratory signs and prevail in the clinical picture of infection. Patients with chronic inflammatory bowel diseases receiving immunosuppressive therapy are at elevated risk of severe COVID-19 progression. The new coronavirus infection may induce liver damage with increased transaminase activity.Conclusion. Association of digestive system lesions with COVID-19 remains understudied and requires further research.
Publisher
Russian Gastroenterolgocial Society
Reference40 articles.
1. Interim methodological guidelines «Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)» (In Russ.) URL: rosminzdrav.ru/ministry/med_covid19.
2. Gu J., Han, B., Wang J. COVID-19: gastrointestinal manifestations and potential fecal–oral transmission. Gastroenterology. 2020;158(6):1518–19. DOI: 10.1053/j.gastro.2020.02.054.
3. Holshue M.L., DeBolt C., Lindquist S., Lofy K.H., Wiesman J., Bruce, et al. First case of 2019 novel coronavirus in the United States. N Engl J Med. 2020 Mar 5;382(10):929–36. DOI: 10.1056/NEJMoa2001191
4. Xiao F., Tang M., Zheng X. Liu Y., Li X., Shan H. Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology. 2020; 158(6):1831–33. DOI:10.1053/j.gastro.2020.02.055
5. Zhang W., Du R.H., Li B., Xu D., Wang J., Li Z., Lin J. Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes. Emerg Microbes Infect 2020;9(1):386–9. DOI:10.1080/22221751.2020.1729071
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