DNA Binding and Topoisomerase I Poisoning Activities of Novel Disaccharide Indolocarbazoles

Author:

Facompre Michaël,Carrasco Carolina,Colson Pierre,Houssier Claude,Chisholm John D.,Van Vranken David L.,Bailly Christian

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference34 articles.

1. Syntheses and Biological Activities (Topoisomerase Inhibition and Antitumor and Antimicrobial Properties) of Rebeccamycin Analogues Bearing Modified Sugar Moieties and Substituted on the Imide Nitrogen with a Methyl Group

2. Novel indolocarbazole compound 6-N-formylamino-12,13-dihydro-1, 11-dihydroxy-13-(β-d-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4-c]carbazole-5,7-(6H)-dione (NB-506): its potent antitumor activities in mice.;Arakawa;Cancer Res,1995

3. New developments in antitumor anthracyclines

4. Formaldehyde-Induced Alkylation of a 2‘-Aminoglucose Rebeccamycin Derivative to Both A·T and G·C Base Pairs in DNA

5. Intercalation into DNA is not required for inhibition of topoisomerase I by indolocarbazole antitumor agents.;Bailly;Cancer Res,1999

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