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Identification of Transdominant-Negative Genetic Suppressor Elements Derived from hMSH2 That Mediate Resistance to 6-Thioguanine

  • Published:2002-11-01 Issue:5 Volume:62 Page:1198-1206
  • ISSN:0026-895X
  • Container-title:Molecular Pharmacology
  • language:en
  • Short-container-title:Mol Pharmacol

Author:

Alas Maida M. de las,Los Gerrit,Lin Xinjian,Kurdi-Haidar Buran,Manorek Gerald,Howell Stephen B.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference39 articles.

1. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

2. Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells.;Aebi;Clin Cancer Res,1997

3. Loss of DNA mismatch repair in acquired resistance to cisplatin.;Aebi;Cancer Res,1996

4. Genetic and biochemical analysis of msh2p-msh6p: role of ATP hydrolysis and msh2p-msh6p subunit interactions in mismatch base pair recognition.;Alani;Mol Cell Biol,1997

5. Rapid emergence of acquired cis-diamminedichloroplatinum(II) resistance in an in vivo model of human ovarian carcinoma.;Andrews;Cancer Commun,1990

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