Tariquidar and Elacridar Are Dose-Dependently Transported by P-Glycoprotein and Bcrp at the Blood-Brain Barrier: A Small-Animal Positron Emission Tomography and In Vitro Study

Author:

Bankstahl Jens P.,Bankstahl Marion,Römermann Kerstin,Wanek Thomas,Stanek Johann,Windhorst Albert D.,Fedrowitz Maren,Erker Thomas,Müller Markus,Löscher Wolfgang,Langer Oliver,Kuntner Claudia

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference43 articles.

1. Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein;Allen;Cancer Res,2003

2. Role Reversal for Anticancer Agents

3. Analysis of the interactions of SDZ PSC 833 ([3′-keto-Bmt1]-Val2]-Cyclosporine), a multidrug resistance modulator, with P-glycoprotein;Archinal-Mattheis;Oncol Res,1995

4. Valproic Acid Is Not a Substrate for P-glycoprotein or Multidrug Resistance Proteins 1 and 2 in a Number of in Vitro and in Vivo Transport Assays

5. Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein

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