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The Influence of Sex, Ethnicity, and CYP2B6 Genotype on Bupropion Metabolism as an Index of Hepatic CYP2B6 Activity in Humans

  • Published:2012-12-13 Issue:3 Volume:41 Page:575-581
  • ISSN:0090-9556
  • Container-title:Drug Metabolism and Disposition
  • language:en
  • Short-container-title:Drug Metab Dispos

Author:

Ilic Katarina,Hawke Roy L.,Thirumaran Ranjit K.,Schuetz Erin G.,Hull J. Heyward,Kashuba Angela D.M.,Stewart Paul W.,Lindley Celeste M.,Chen Mei-Ling

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference30 articles.

1. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes;Chang;Cancer Res,1993

2. Effects of Pregnane X Receptor (NR1I2) and CYP2B6 Genetic Polymorphisms on the Induction of Bupropion Hydroxylation by Rifampin

3. Human Extrahepatic Cytochromes P450: Function in Xenobiotic Metabolism and Tissue-Selective Chemical Toxicity in the Respiratory and Gastrointestinal Tracts

4. Linear Equality Constraints in the General Linear Mixed Model

5. Further characterization of the expression in liver and catalytic activity of CYP2B6;Ekins;J Pharmacol Exp Ther,1998
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