ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel-Reference-Cited by-同舟云学术

ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel

Published:2019-08-19 Issue:4 Volume:96 Page:515-525
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Wu Yu-Sheng,Jiang Janet,Ahmadi Saumel,Lew Alexandria,Laselva Onofrio,Xia Sunny,Bartlett Claire,Ip Wan,Wellhauser Leigh,Ouyang Hong,Gonska Tanja,Moraes Theo J.,Bear Christine E.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference51 articles.

1. Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia;Ahmadi;NPJ Genom Med,2017

2. SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion;Ahmadi;eLife,2018

3. Individualized medicine using intestinal responses to CFTR potentiators and correctors;Beekman;Pediatr Pulmonol,2016

4. Brushed nasal epithelial cells are a surrogate for bronchial epithelial CFTR studies;Brewington;JCI Insight,2018

5. Transducing airway basal cells with a helper-dependent adenoviral vector for lung gene therapy;Cao;Hum Gene Ther,2018

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